This submission belongs to the session b. Combinatorial Synthesis and Automation of the event The 1st International Electronic Conference on Synthetic Organic Chemistry
Published date
01 Sep, 1997
Citation
Florencio Zaragoza Doerwald, Henrik Stephensen, Resin-bound Isothiocyanates and their Synthetic Equivalents as Intermediates for the Solid-Phase Synthesis of Substituted Thiophenes, in Proceedings of The 1st International Electronic Conference on Synthetic Organic Chemistry, 1 November–30 November 1997, MDPI: Basel, Switzerland, doi: 10.3390/ecsoc-1-02055
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Resin-bound Isothiocyanates and their Synthetic Equivalents as Intermediates for the Solid-Phase Synthesis of Substituted Thiophenes
Henrik Stephensen 1
Florencio Zaragoza Doerwald 1
1. Novo Nordisk A/S, Novo Nordisk Park, DK-2760 Maaloev, Denmark
Abstract
Highly reactive, polystyrene-bound thiocarbamoyl chlorides and isothiocyanates have been used as key intermediates in a new, robust solid-phase synthesis of substituted thiophenes.
Keywords
solid-phase synthesis
thiophenes
combinatorial chemistry.
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