EventsThe 13th International Electronic Conference on Synthetic Organic Chemistry
Event submissions
Published
with-doi10.3390/ecsoc-13-00209
This submission belongs to the session c. Bioorganic Chemistry and Natural Products of the event The 13th International Electronic Conference on Synthetic Organic Chemistry
Published date
01 Nov, 2009
Citation
Mihaiela Andoni, Maria Elena Grad, Anca Dragomirescu, Georgeta Maria Simu, SYNTHESIS AND IN VIVO IMAGISTIC SKIN EVALUATION OF A NEW DISAZO DYE DERIVED FROM 4,4'-DIAMINOSTILBENE-2,2'- DISULFONIC ACID, in Proceedings of The 13th International Electronic Conference on Synthetic Organic Chemistry, 1 November–30 November 2009, MDPI: Basel, Switzerland, doi: 10.3390/ecsoc-13-00209
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SYNTHESIS AND IN VIVO IMAGISTIC SKIN EVALUATION OF A NEW DISAZO DYE DERIVED FROM 4,4'-DIAMINOSTILBENE-2,2'- DISULFONIC ACID

Mihaiela Andoni 1
Maria Elena Grad 2
Anca Dragomirescu 1
Georgeta Maria Simu 1
1. University of Medicine and Pharmacy Victor Babeş Timişoara, Faculty of Pharmacy, Piata Eftimie Murgu 2-4, RO-300034 Timişoara, Romania
2. Institute of Chemistry Timisoara of the Romanian Academy, B-dul Mihai Viteazul 24, 300223 Timişoara, Romania
Abstract
The synthesis of a new disazo dyes containing 4,4'-diaminostilbene-2,2'-disulfonic acid as middle component is presented. The synthesized dye was analyzed by thin layer chromatography (TLC), electronic spectra (VIS) and HPLC technique. The structure was elucidated by FT/IR and 13CNMR spectroscopy. The colouristic evaluation of the synthesized dye indicates that this dye could be ranged as a direct dye, suitable for application on cellulosic substrates. Further, an in vivo imagistic skin study was performed in order to evaluate the individual human skin tolerance for this new disazo dye.
Keywords
Azo direct dyes
4
4’-diaminostilbene-2,2’-disulfonic acid
Colouristic properties
Imagistic skin evaluation
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