Microwave-assisted synthesis of Cd (II) complex of 4-pyridinecarboxaldehyde thiosemicarbazone

Thiosemicarbazones, obtained by condensation of thiosemicarbazide with suitable aldehydes or ketones, act as ligand in the preparation of their complexes. They bind to the metal through N and S atoms. Their metal complexes may have biological properties. In this work, di chloro 4-pyridinecarboxaldehyde thiosemicarbazone cadmium (II) was synthesized by an efficient and facile microwave heating technique. The reaction was performed using CdCl2.H2O as metal source and 4-pyridinecarboxaldehyde thiosemicarbazone as ligand in 1:1 molar ratio in EtOH under microwave irradiation with the power of 100 W for 30 sec. The progress of the reaction was monitored by TLC. The product was characterized by Fourier transform infrared (FT-IR), 1H-, 13C- NMR spectroscopy and elemental analysis.   Spectroscopic data: IR (KBr, cm-1): 3440(m), 3317(m), 3172(m), 1541(s), 1326(s), 823(m), 655(m), 530(m). 1HNMR (DMSO-d6, ppm) δH: 7.78(s, 2H), 8.21(s, 1H), 8.39(s, 1H), 8.57 (d, 2H), 11.69 (s,1H). 13CNMR (DMSO-d6, ppm) δC: 121.88, 139.93, 142.66, 150.30, 178.68. Elemental analysis: Anal. Calc. for C7H8N4SCdCl2: C, 23.14; H, 2.20; N, 15.42.  Found C,  24.29; H, 2.18; N, 15.27