This submission belongs to the session a. General Organic Synthesis of the event The 17th International Electronic Conference on Synthetic Organic Chemistry
Published date
31 Oct, 2013
Citation
Tarik E. Ali, Salah A. Abdel-Aziz, Somaya M. El-Edfawy, El-Hossain A. Mohamed, Somaia M. Abdel-Kariem, SYNTHESIS AND BIOLOGICAL EVALUATIONS OF A SERIES OF NOVEL AZOLYL, AZINYL, PYRANYL, CHROMONYL AND AZEPINYL PHOSPHONATES, in Proceedings of The 17th International Electronic Conference on Synthetic Organic Chemistry, 1 November–30 November 2013, MDPI: Basel, Switzerland, doi: 10.3390/ecsoc-17-a046
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SYNTHESIS AND BIOLOGICAL EVALUATIONS OF A SERIES OF NOVEL AZOLYL, AZINYL, PYRANYL, CHROMONYL AND AZEPINYL PHOSPHONATES
Tarik E. Ali 1
Salah A. Abdel-Aziz 1
Somaya M. El-Edfawy 1
El-Hossain A. Mohamed 1
Somaia M. Abdel-Kariem 1
1. Department of Chemistry, Faculty of Education, Ain Shams University, Roxy, Cairo, Egypt
Abstract
A faciles ynthetic methodology of novel azolyl, azinyl and azepinyl phosphonates ascyclic α-aminophosphonates was described. Chromonyl α-aminophosphonates,γ-pyranyl and γ-pyridinyl phosphonates were also prepared. The methodologydepends on reaction of 6-methyl-3-formylchromone, nitrogen and carbon nucleophiles in thepresence of diethyl phosphite in one-pot three component under solvent-freeconditions. The products were evaluated for their antimicrobial activities andantioxidant properties.
Keywords
α-Aminophosphonate
Phosphonate
Chromone
Ring opening and Ring closure
Antimicrobial
Antioxidant
Manuscript
The manuscript.pdf
Poster
The manuscript.pdf
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