Events The 2nd International Online Conference on Toxics

Event submissions

Published

This submission belongs to the session 5. Exploring Non-Model Species for Ecotoxicology of the event The 2nd International Online Conference on Toxics

Published date

04 Sep, 2025

Academic Editor

Carlos Barata

Citation

Telma Esteves, Margarida Vilaça, Rosária Seabra, Fernanda Malhão, Eduardo Rocha, Célia Lopes, Optimisation of three-dimensional cultures of the RTL-W1 liver cell line to model polycyclic aromatic hydrocarbon effects on liver detoxification, in Proceedings of The 2nd International Online Conference on Toxics, 8 September–10 September 2025, MDPI: Basel, Switzerland

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Optimisation of three-dimensional cultures of the RTL-W1 liver cell line to model polycyclic aromatic hydrocarbon effects on liver detoxification

Telma Esteves ^1,2

Margarida Vilaça ^1,2

Rosária Seabra ^1,2

Fernanda Malhão ^1,2

Eduardo Rocha ^1,2

Célia Lopes ^1,2

1. Team of Animal Morphology and Toxicology, CIIMAR/CIMAR – Interdisciplinary Centre of Marine and Environmental Research, University of Porto, Porto, Portugal

2. Laboratory of Histology and Embryology, Department of Microscopy, ICBAS – School of Medicine and Biomedical Sciences, University of Porto, Porto, Portugal

Abstract

Keywords

3D culture

benzo(k)fluoranthene

global warming

liver in vitro models

PAHs

RTL-W1

spheroids