EventsThe 18th International Electronic Conference on Synthetic Organic Chemistry
Event submissions
Published
with-doi10.3390/ecsoc-18-b008
This submission belongs to the session b. Bioorganic, Medicinal and Natural Products Chemistry of the event The 18th International Electronic Conference on Synthetic Organic Chemistry
Published date
31 Oct, 2014
Citation
Vitalis Aondoaver Anoh, Stephen Attah Agbo, Peter Iorhemba Swande, Antimicrobial Evaluation of Some Monoazaphenoxazines Carboxamides: A Structural Activity Relationship (SAR), in Proceedings of The 18th International Electronic Conference on Synthetic Organic Chemistry, 1 November–30 November 2014, MDPI: Basel, Switzerland, doi: 10.3390/ecsoc-18-b008
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Antimicrobial Evaluation of Some Monoazaphenoxazines Carboxamides: A Structural Activity Relationship (SAR)

Vitalis Aondoaver Anoh 1
Stephen Attah Agbo 1
Peter Iorhemba Swande 1
1. Division of Organic Chemistry, Department of Chemistry, Benue State University, Makurdi, Nigeria
Abstract
A series of some monoazaphenoxzines carboxamides evaluated against Salmonella typhi, Stapyhlococcus aureus, Escherichia coli, Klebsiella pneumonia, Streptococcus pyogene and Pseudomonas aeruginosa in a micro dilution broth assay. The results obtained showed that these compounds exhibited considerable antibacterial activity depending on the substituents on the monoazaphenoxazine ring. The best activity were obtained with substituents containing nitro-group as in 3-(-4-nitrobenzamido)-1-azaphenoxazine and chloride-group as in 3-trichloromethanamido-1-azaphenoxazine
Keywords
Antibacterial activity
synthesis
Phenoxazine derivatives
nickel catalyst
Manuscript
Anoh and others antimicrobial studies.pdf
Poster
Anoh and others antimicrobial studies.pdf
Anoh and others antimicrobial studies.pdf
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