This submission belongs to the session b. Bioorganic, Medicinal and Natural Products Chemistry of the event The 18th International Electronic Conference on Synthetic Organic Chemistry
Published date
03 Nov, 2014
Citation
Fatemeh Fayyaz, Rahmatollah Rahimi, Mehdi Rassa, Comparison of Minimal Inhibitory Concentration of Porphyrin Compounds Against Bacillus Subtilis Under Irradiation With Visible Light, in Proceedings of The 18th International Electronic Conference on Synthetic Organic Chemistry, 1 November–30 November 2014, MDPI: Basel, Switzerland, doi: 10.3390/ecsoc-18-b024
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Comparison of Minimal Inhibitory Concentration of Porphyrin Compounds Against Bacillus Subtilis Under Irradiation With Visible Light
Fatemeh Fayyaz 1
Rahmatollah Rahimi 1
Mehdi Rassa 2
1. Iran University of Science and Technology
2. Department of Biology, Faculty of Science, University of Guilan , Rasht, Iran
Abstract
In this study, the effect of meso-tetrakis (N-methyl-3-pyridyl)porphyrin (TMPyP(3)), meso-tetrakis (4-N, N, N-trimethylanilinium) porphyrin (TAPP) and their zinc compounds irradiated with visible light, on a Gram positive bacterium, Bacillus subtilis, was investigated and compared. MIC, MBC and inhibition zones produced by these compounds were determined and the bacteria numbers were counted. The results indicate that TAPP and its zinc compound have more effective inhibitory activity than others against this bacterium.
Keywords
Bacillus subtilis
photo-inactivation
Tetra-cationic porphyrin
minimal inhibitory concentration
Manuscript
conference2.pdf
Structural Modifications on Natural-based Products: Synthetic Strategies and Biological Applications