EventsThe 1st International Online Conference on Healthcare
Published
This submission belongs to the session S5. Generative AI in Clinical Practice—Evidence-Based Evaluation of Diagnostic and Therapeutic Applications of the event The 1st International Online Conference on Healthcare
Published date
20 Mar, 2026
Academic Editor
author-avatarLorraine Evangelista
Citation
Ghazenfer Mansoor, Evaluating Generative AI in Clinical Workflows: A Practical Framework for Safe and Effective Deployment, in Proceedings of The 1st International Online Conference on Healthcare, 25 March–26 March 2026, MDPI: Basel, Switzerland
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Evaluating Generative AI in Clinical Workflows: A Practical Framework for Safe and Effective Deployment

1. AI & HealthTech Innovation, Technology Rivers, Reston Virginia, 20190, USA, USA
Abstract

As generative AI rapidly evolves, healthcare organizations face growing pressure to evaluate these technologies and integrate them into clinical workflows safely and effectively. While clinical validation remains the responsibility of medical experts, technology teams play a critical role in ensuring that generative AI tools are designed, tested, and deployed in ways that support accurate, reliable, and ethical use in diagnostic and therapeutic contexts. This presentation offers a practical, real-world framework for assessing generative AI applications from the perspective of health-tech product development and system implementation.

Drawing on experience building AI-enabled digital health solutions, this session outlines key technological evaluation steps, including data quality assessment, model behavior testing, hallucination monitoring, and bias detection. It further examines requirements for integrating generative AI into existing health IT environments, such as EHR systems, telehealth platforms, and patient-facing digital tools. Emphasis is placed on human-in-the-loop design, safety guardrails, auditability, and operational monitoring—elements that ensure clinical teams can adopt AI tools with confidence and maintain control over decision-making processes.

The talk also highlights common challenges observed during real deployments, such as workflow misalignment, context loss, interoperability gaps, and regulatory readiness. Practical strategies will be shared for mitigating these issues through robust architecture design, model evaluation pipelines, and continuous performance oversight.

This session is intended for healthcare leaders, clinical innovators, and health-tech professionals seeking to understand how generative AI systems can be responsibly introduced into clinical environments. Attendees will leave with a clear, actionable methodology for evaluating and preparing generative AI tools for safe deployment, enabling technology teams and clinicians to work together to unlock real clinical value while maintaining patient safety and regulatory compliance.

Keywords
Generative AI
Clinical workflows
Health-tech implementation
AI evaluation
Human-in-the-loop
Model safety
Workflow integration
Diagnostic support tools
Responsible AI deployment
Healthcare technology systems
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