Events1st Electronic Conference on Molecular Science
Published
This submission belongs to the session d. Effect of Radiation on Cell Function of the event 1st Electronic Conference on Molecular Science
Published date
13 Oct, 2015
Citation
Fatemeh Fayyaz, Mehdi Rassa, Rahmatollah Rahimi, Reza Hedayat Yaghoobi, The effect of irradiation time on the viability of Bacillus subtilis by cationic porphyrin compounds, in Proceedings of 1st Electronic Conference on Molecular Science, 15 October–22 October 2015, MDPI: Basel, Switzerland, doi: 10.3390/ecms-1-d001
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The effect of irradiation time on the viability of Bacillus subtilis by cationic porphyrin compounds

Mehdi Rassa 2
Reza Hedayat Yaghoobi 3
1. Iran University of Science and Technology
2. Department of Biology, Faculty of Science, University of Guilan , Rasht, Iran
3. Medical University of Kermanshah, Kermanshah, Iran
Abstract

The photodynamic therapy (PDT) is a combination of using a photosensitizer agent, light and oxygen that can cause oxidative cellular damage. This technique is applied in several cases, including microbial control. Various porphyrin and metalloporphyrin compounds are used as photosensitizer agents. In this study, the effect of a tetra-cationic porphyrin and its zinc compound was investigated on Bacillus subtilis under irradiation with a tungsten lamp as a visible light and the illumination time varied from 0 min to 30 min. Increasing the illumination time reduced the colony number, through the disorganisation of the bacterial cell wall. 

Keywords
Bacillus subtilis
Photobactericidal
Tetra-cationic porphyrin
Visible light.
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