EventsMOL2NET'15, Conference on Molecular, Biomed., Comput. & Network Science and Engineering, 1st ed.
Published
This submission belongs to the session 05. CHEMBIO.MOL-01: Org. Chem., Med. Chem., Pharm. Industry, & Mol. Biol., Congress, Paris, France-Galveston, USA, 2023., Rostock, Germany-Bilbao, Spain-Galveston, Texas, USA, 2015 of the event MOL2NET'15, Conference on Molecular, Biomed., Comput. & Network Science and Engineering, 1st ed.
Published date
04 Dec, 2015
Citation
Mohamed Ibrahim Elzagheid, Fluorinated Nucleosides (Mini Review), in Proceedings of MOL2NET'15, Conference on Molecular, Biomed., Comput. & Network Science and Engineering, 1st ed., 5 December–15 December 2015, MDPI: Basel, Switzerland, doi: 10.3390/MOL2NET-1-a012
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Fluorinated Nucleosides (Mini Review)

1. Chemical and Processing Engineering Technology Department (Industrial Chemistry), Jubail Industrial College, PO Box 10099, Jubail Industrial City 31961, Kingdom of Saudi Arabia Email: elzagheid_m@jic.edu.sa, elzagheid66@yahoo.com
Abstract

In this mini review different methods for the preparation of base- and sugar-fluorinated nucleoside will be discussed and the use of different fluorinating agents will be briefly elaborated within the text.  Introduction of fluorine substituent into pyrimidine and purine nucleosides surely  lead to dramatic change in the over all chemical reactivity. In fact, there are many examples of the base- and sugar-fluorinated nucleosides that make a great impact on chemistry, biochemistry, and drug discovery.

Keywords
Nucleosides
fluorinated nucleosides
fluorinating agents.
Manuscript
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