EventsThe 1st International Online Conference on Dentistry
Published
This submission belongs to the session S6. Lasers in Dentistry of the event The 1st International Online Conference on Dentistry
Published date
02 Oct, 2026
Academic Editor
author-avatarSamir Nammour
Citation
Giuseppe Murano, Giusppe D'Albis, Marta Forte, Maria Grazia Leone, Alice Annicchiarico, Simone Egitto, Saverio Capodiferro, Laser-Assisted Pre-Prosthetic Frenulotomy in Medically Complex Anticoagulated Edentulous Patients: A Prospective Clinical Study, in Proceedings of The 1st International Online Conference on Dentistry, 7 October–9 October 2026, MDPI: Basel, Switzerland
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Laser-Assisted Pre-Prosthetic Frenulotomy in Medically Complex Anticoagulated Edentulous Patients: A Prospective Clinical Study

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Alice Annicchiarico 1
Simone Egitto 1
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1. Department of Interdisciplinary Medicine, University of Bari “Aldo Moro”, 70121 Bari, Italy
Abstract

Introduction

Restrictive maxillary buccal frena are anatomo-functional alterations of the oral soft tissues that may reduce vestibular depth, impair denture extension, and compromise the retention and stability of complete removable prostheses. Conventional surgical correction may be associated with increased bleeding and postoperative discomfort, particularly in medically compromised patients receiving anticoagulant therapy. The aim of this prospective study was to evaluate the clinical effectiveness and safety of diode laser-assisted frenulotomy performed before complete denture rehabilitation in medically complex edentulous patients.

Materials and Methods

A prospective clinical study was conducted at the Department of Dentistry, University of Bari. Edentulous patients under chronic anticoagulant therapy with Warfarin, 5 mg/die, requiring complete denture rehabilitation and presenting with restrictive maxillary buccal frena underwent bilateral frenulotomy under local anesthesia. A diode laser with bare fiber of 300 µm, a wavelength of 810–980 nm, in a continuous-wave mode, and power of 1.5 Watt was used. Clinical outcomes, intraoperative bleeding, postoperative healing, and surgical complications were evaluated during follow-up.

Results

Five patients were prospectively enrolled and treated in this study. Laser-assisted surgery provided effective intraoperative hemostasis, reducing hemorrhagic risk and improving visualization of the operative field in all treated patients. Complete soft-tissue healing and adequate vestibular depth were observed at the one-month follow-up. No intraoperative or postoperative complications, delayed healing, or adverse events related to laser treatment were recorded, allowing successful completion of prosthetic rehabilitation.

Conclusions

Diode laser-assisted frenulotomy represents a safe and minimally invasive pre-prosthetic procedure for medically complex anticoagulated edentulous patients. The technique provides predictable hemostasis, promotes favorable soft-tissue healing, facilitates prosthetic rehabilitation, and may represent a reliable alternative to conventional scalpel surgery in high-risk clinical conditions.

Keywords
Laser
pre-prosthetic procedure
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