Event submissions
Published
This submission belongs to the session b. Bioorganic, Medicinal and Natural Products Chemistry of the event The 20th International Electronic Conference on Synthetic Organic Chemistry
Published date
01 Nov, 2016
Citation
Tannya Ibarra-Rivera, Veronica Mayela Rivas-Galindo, Ernesto Torres-Lopez, David Arturo Silva-Mares, Yolanda Daniela Estrada-Chavarria, Semi-Synthesis and Anti-Herpetic Activity of New Riolozatrione Derivatives, in Proceedings of The 20th International Electronic Conference on Synthetic Organic Chemistry, 1 November–30 November 2016, MDPI: Basel, Switzerland, doi: 10.3390/ecsoc-20-b001
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Semi-Synthesis and Anti-Herpetic Activity of New Riolozatrione Derivatives
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Tannya Ibarra-Rivera 1
Veronica Mayela Rivas-Galindo 1
Ernesto Torres-Lopez 1
David Arturo Silva-Mares 1
Yolanda Daniela Estrada-Chavarria 1
1. Universidad Autonoma de Nuevo Leon, Facultad de Medicina.
Abstract
Riolozatrione is a natural diterpene isolated form Jatropha dioica to which anti-viral activity is attributed. In this work we report the synthesis of 5 new derivatives and its anti-herpetic evaluation. Riolozatrione posses a unique diterpene core attractive for chemical modification. Conjugate ketone was selectively hydrogenated whereas sodium borohydride draws for three different riolozatrione analogues.
Keywords
Manuscript
Semi-Synthesis of New Riolozatrione Derivatives.pdf
Poster
ECSOC 2016 Tannya Ibarra.pdf
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