Events 2nd International Electronic Conference on Medicinal Chemistry

Event submissions

Published

This submission belongs to the session A. ECMC-2 of the event 2nd International Electronic Conference on Medicinal Chemistry

Published date

01 Nov, 2016

Citation

Cheng-Deng Kuo, En-Tung Tsai, Ming-Che Chang, Jin-Yi Wu, Hui-Fen Liao, Yu-Jen Chen, <strong>N-Farnesyl-norcantharimide Inhibits Progression of Human Leukemic Jurkat T Cells Through Up-regulation of Tumor Suppressor Gene and Down-regulation of Steroid Biosynthesis, Metabolic Pathways, and Fatty Acid Metabolism</strong>, in Proceedings of 2nd International Electronic Conference on Medicinal Chemistry, 1 November–30 November 2016, MDPI: Basel, Switzerland, doi: 10.3390/ecmc-2-A007

FaceBook

Twitter

N-Farnesyl-norcantharimide Inhibits Progression of Human Leukemic Jurkat T Cells Through Up-regulation of Tumor Suppressor Gene and Down-regulation of Steroid Biosynthesis, Metabolic Pathways, and Fatty Acid Metabolism

En-Tung Tsai ¹

Ming-Che Chang ¹

Jin-Yi Wu ²

Hui-Fen Liao ³

Yu-Jen Chen ⁴

Cheng-Deng Kuo ⁵

1. Laboratory of Biophysics, Department of Medical Research, Taipei Veterans General Hospital, Taipei, 112 Taiwan

2. Department of Microbiology, Immunology and Biopharmaceutics, College of Life Sciences, National Chiayi University, Chiayi, 600 Taiwan

3. Department of Molecular Biology and Biochemistry, National Chiayi University, Chiayi, 600 Taiwan

4. Department of Radiation Oncology, Mackay Memorial Hospital, Taipei, 104 Taiwan

5. Chest Medicine and Physiological Signals Research Center, Changhua Christian Hospital, Changhua, 500 Taiwan

Abstract

Keywords

N-farnesyl-norcantharimide - Jurkat T cells – Apoptosis - Next generation sequencing - Tumor suppressor gene - Biosynthesis