EventsThe 2nd International Electronic Conference on Medicinal Chemistry and Pharmaceutics
Published
This submission belongs to the session S4. Natural Products and Biopharmaceuticals of the event The 2nd International Electronic Conference on Medicinal Chemistry and Pharmaceutics
Published date
28 Oct, 2026
Academic Editor
author-avatarMary J. Meegan
Citation
Rita Favas, Andreia Peixoto, Hugo Almeida, Domingos Ferreira, Ana Catarina Silva, Antioxidant Potential of Oil Shrimp Shells Extracts, in Proceedings of The 2nd International Electronic Conference on Medicinal Chemistry and Pharmaceutics, 1 November–30 November 2026, MDPI: Basel, Switzerland
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Antioxidant Potential of Oil Shrimp Shells Extracts

Rita Favas 1,2
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Domingos Ferreira 1,2
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1. MEDTECH - Pharmaceutical Technology Laboratory, Faculty of Pharmacy, University of Porto, Porto, 4050-313, Portugal
2. UCIBIO i4HB, Faculty of Pharmacy, University of Porto, Porto, 4050-313, Portugal
3. LAQV-REQUIMTE, Department of Chemistry and Biochemistry, Faculty of Sciences, University of Porto, Porto, 4169-007, Portugal
4. Mesosystem, Research & Investments by Spinpark, Guimarães, 4805-017, Portugal
5. LAQV-REQUIMTE, Department of Chemical Sciences, Faculty of Pharmacy, University of Porto, Porto, 4050-313, Portugal
6. FP-I3ID (Institute for Research, Innovation and Development), FP-BHS (Biomedical and Health Sciences Research Unit), Faculty of Health Sciences, University Fernando Pessoa, Porto, 4200-150, Portugal
Abstract

Introduction: Shrimp shells are an abundant by-product of the seafood industry and are frequently discarded, contributing to environmental concerns. Nevertheless, they contain valuable bioactive compounds with potential antioxidant properties. This study aimed to evaluate the antioxidant activity of shrimp shell extracts obtained using sunflower oil and to assess their potential as sustainable sources of natural antioxidants.

Methods: Shrimp shells were collected, cleaned, dried, and subjected to ultrasound-assisted extraction using sunflower oil as the extraction medium. The antioxidant activity of the resulting extracts was evaluated using the DPPH and ABTS radical scavenging assays. Results were expressed as percentage of radical scavenging activity and compared with ascorbic acid used as a reference antioxidant.

Results: The shrimp shell extracts demonstrated substantial radical scavenging activity at the tested concentrations. In the DPPH assay, the extract showed 82.15 ± 0.33% radical scavenging activity at 5.4 µg/mL, whereas ascorbic acid reached 31.75 ± 0.84% at the same concentration. In the ABTS assay, the extract exhibited 51.78 ± 0.31% radical scavenging activity at 3.90 µg/mL, compared with 44.61 ± 0.92% for the reference antioxidant at the same concentration.

Conclusions: These findings highlight the antioxidant potential of shrimp shell extracts obtained using sunflower oil and support the valorization of shrimp-processing by-products as sources of natural bioactive compounds. The results provide a basis for further development of these extracts through their incorporation into nanostructured lipid carriers (NLC), with the aim of exploring their potential for cosmetic applications.

Keywords
shrimp shells; natural bioactive compounds; antioxidant activity; ultrasound-assisted extraction; marine by-products
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