EventsThe 20th International Electronic Conference on Synthetic Organic Chemistry
Published
This submission belongs to the session a. General Organic Synthesis of the event The 20th International Electronic Conference on Synthetic Organic Chemistry
Published date
01 Nov, 2016
Citation
Angel Rentería-Gómez, Rocío Gámez-Montaño, Synthesis of 1,5-disubstituted tetrazoles containing propargyl moiety, in Proceedings of The 20th International Electronic Conference on Synthetic Organic Chemistry, 1 November–30 November 2016, MDPI: Basel, Switzerland, doi: 10.3390/ecsoc-20-a054
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Synthesis of 1,5-disubstituted tetrazoles containing propargyl moiety

1. Universidad de Guanajuato
Abstract

A series of nine new 1,5-disubstituted-1H-tetrazoles were synthesized via MCR Ugi-azide in moderate to excellent yields (80 - 95%), using propargyl amine as component varying the aldehyde and isocyanide components. 1,5-DS-T are useful heterocyclic moieties present in many bioactive compounds and drugs. Morever 1,5-DS-T are used as bidentate ligands, in coordination chemistry, metal-organic framework science, bioimaging, photo-imaging, explosives, propellants, high energy materials.

Keywords
Ugi-azide
tetrazoles
MCR
isocyanide
Manuscript
Poster
Presentación Ángel Rentería.pdf
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