EventsThe 14th International Electronic Conference on Synthetic Organic Chemistry
Event submissions
Published
with-doi10.3390/ecsoc-14-00431
This submission belongs to the session c. Microwave Assisted Synthesis of the event The 14th International Electronic Conference on Synthetic Organic Chemistry
Published date
30 Oct, 2010
Citation
Mostafa Safari, Shahrzad Javanshir, A new catalyst-free microwave-assisted one-pot four-component synthesis of 1,4-dihydroquinolines in aqueous media, in Proceedings of The 14th International Electronic Conference on Synthetic Organic Chemistry, 1 November–30 November 2010, MDPI: Basel, Switzerland, doi: 10.3390/ecsoc-14-00431
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A new catalyst-free microwave-assisted one-pot four-component synthesis of 1,4-dihydroquinolines in aqueous media

Mostafa Safari 1
Shahrzad Javanshir 1
1. Heterocyclic Chemistry Research Laboratory, Department of Chemistry,
Abstract
A novel rapid one-pot four-component reaction between resorcinol, aromatic aldehydes, malononitrile and ammonium acetate in aqueous media was performed under microwave irradiation for the synthesis of 1,4-dihydroquinoline derivatives. The main advantages of this method are the short reaction time, high yields, despite absence of any catalyst, and simple work-up.
Keywords
1,4-dihydroquinolines
Multicomponent reaction
Microwave-assisted
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