Events The 14th International Electronic Conference on Synthetic Organic Chemistry

Event submissions

Published

This submission belongs to the session a. General Organic Synthesis of the event The 14th International Electronic Conference on Synthetic Organic Chemistry

Published date

25 Oct, 2010

Citation

M. Sameiro T. Gonçalves, Susana P. G. Costa, Ana M. Piloto, Release of model amino acids by ester linkage photolysis from fused 2-oxo-2H-benzopyranyl conjugates, in Proceedings of The 14th International Electronic Conference on Synthetic Organic Chemistry, 1 November–30 November 2010, MDPI: Basel, Switzerland, doi: 10.3390/ecsoc-14-00438

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Release of model amino acids by ester linkage photolysis from fused 2-oxo-2H-benzopyranyl conjugates

M. Sameiro T. Gonçalves ¹

Susana P. G. Costa ¹

Ana M. Piloto ¹

1. Centro de Química, Universidade do Minho, Campus de Gualtar, 4710-057 Braga, Portugal

Abstract

Valine and phenylalanine were used as model amino acids for the synthesis of ester conjugates with a fused oxobenzopyran, in order to evaluate its applicability as a photocleavable protecting group for solution phase organic and peptide synthesis. The behaviour of the corresponding conjugates towards photocleavage was evaluated by irradiation in methanol/HEPES buffer (80:20) and acetonitrile/HEPES buffer (80:20) solutions, in a photochemical reactor at different wavelengths (300 and 350 nm), followed by HPLC/UV monitoring.

Keywords

SYNTHESIS OF DICOMPARTIMENTAL SCHIFF BASE LIGANDS. CRYSTAL STRUCTURE OF (N-N'-BIS(3- METHOXY or 3-ETHOXYSALICYLIDENE)-1,2-DIAMINE-2-METHYLPROPANE

Quantitative Synthesis of α-Amino Nitriles through Strecker Reaction of Aldimines with TMSCN Catalyzed by Tetrabutylammonium phthalimide-N-oxyl