Events The 14th International Electronic Conference on Synthetic Organic Chemistry

Event submissions

Published

This submission belongs to the session c. Microwave Assisted Synthesis of the event The 14th International Electronic Conference on Synthetic Organic Chemistry

Published date

31 Oct, 2010

Citation

Jaroslaw Polanski, Robert Musiol, Maciej Serda, New thiosemicarbazones based on quinoline scaffold as anticancer iron chelators, in Proceedings of The 14th International Electronic Conference on Synthetic Organic Chemistry, 1 November–30 November 2010, MDPI: Basel, Switzerland, doi: 10.3390/ecsoc-14-00441

Facebook

Twitter

New thiosemicarbazones based on quinoline scaffold as anticancer iron chelators

Jaroslaw Polanski ¹

Robert Musiol ¹

Maciej Serda ¹

1. University of Silesia, Institute of Chemistry, Szkolna 9, 40-007 Katowice, POLAND.

Abstract

Novel quinoline derivatives was designed as anticancer iron chelators. Structurally they combine active moieties of known quinoline and thiosemicarbazone bioeffectors. For the synthetic part of study we applied microvawe assisted techniques MAOS. Resulted compounds exhibited interesting anticancer activities against HCT116 cancer cells.

Keywords

Thiosemicarbazones

quinoline

anticancer

microwave

Novel fused oxobenzopyrano[6,7-d]oxazoles as light-triggered protecting groups for carboxylic acids

Synthesis of 5H-pyrido[4,3-b]indole by a modification of Pomeranz-Fritsch isoquinoline synthesis