EventsThe 14th International Electronic Conference on Synthetic Organic Chemistry
Event submissions
Published
with-doi10.3390/ecsoc-14-00448
This submission belongs to the session c. Microwave Assisted Synthesis of the event The 14th International Electronic Conference on Synthetic Organic Chemistry
Published date
28 Oct, 2010
Citation
Nguyen Thuy Linh, Do Thi Thuy Giang, Hoang Thi Kim Van, Nguyen Dinh Thanh, SYNTHESIS OF AROMATIC (PER-O-ACETYL-b-LACTOSYL)-THIOSEMICARBAZONES, in Proceedings of The 14th International Electronic Conference on Synthetic Organic Chemistry, 1 November–30 November 2010, MDPI: Basel, Switzerland, doi: 10.3390/ecsoc-14-00448
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SYNTHESIS OF AROMATIC (PER-O-ACETYL-b-LACTOSYL)-THIOSEMICARBAZONES

Nguyen Thuy Linh
Do Thi Thuy Giang
Hoang Thi Kim Van
Nguyen Dinh Thanh
Abstract
A series of per-O-acetyl-b-D-glycosyl thiosemicarbazones 4 and 5 of benzaldehydes and acetophenones were obtained from reaction of per-O-acetyl-b-maltosyl thiosemicarbazide 1 with corresponding carbonyl compounds (2 and 3) in ethanol or acetic acid as solvent using microwave-assisted method. The positions of the magnetic resonance signals in their NMR spectra and the substituent's nature have been indicated by Hammett's regression. The b anomeric configuration of these thiosemicarbazones was confirmed on the basis of the coupling constant J = 9.0–9.5 Hz between proton NH-4 of thiosemicarbazone bond and proton H-1' in maltose component. Structures of thiosemicarbazones were confirmed by spectroscopic methods
Keywords
Synthesis of Acetaminophen by Liquid Phase Beckmann Rearrangement of 4-Hydroxyacetophenone Oxime over Nano-Ordered Zn-MCM-41
Different influence of polyoxygenation on the catalytic activity of amido vs. amino isoborneols