Events The 21st International Electronic Conference on Synthetic Organic Chemistry

Event submissions

Published

This submission belongs to the session B. Bioorganic, Medicinal and Natural Products Chemistry of the event The 21st International Electronic Conference on Synthetic Organic Chemistry

Published date

03 Nov, 2017

Citation

AGBO STEPHEN ATTAH, SWANDE PETER IOREMBER, ANOH VITALIS AONDOAVER, In vitro Antimicrobial activity of Newly Synthesized Monoazaphenothiazine Derivatives., in Proceedings of The 21st International Electronic Conference on Synthetic Organic Chemistry, 1 November–30 November 2017, MDPI: Basel, Switzerland, doi: 10.3390/ecsoc-21-04715

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In vitro Antimicrobial activity of Newly Synthesized Monoazaphenothiazine Derivatives.

AGBO STEPHEN ATTAH ¹

SWANDE PETER IOREMBER ²

ANOH VITALIS AONDOAVER ¹

1. Organic Chemistry Unit, Department of Chemistry, Faculty of Science, Benue State University, Makurdi, Nigeria

2. Department of Basic Sciences, Akperan Orshi College of Agriculture, Yandev, Gboko, Nigeria

Abstract

Abstract The antimicrobial activity of newly synthesized linear monoazaphenothiazine derivatives; 3-benzamido-1-azaphenothiazine, 3-trifluoromethamido-1-azaphenothiazine, 3-trichloromethanamido-1-azaphenothiazine and 3-(4-nitrobenzamido)-1- azaphenothiazine have been evaluated against bacteria and fungal strains. Results showed that most of the synthesized linear monoazaphenothiazine derivatives were significantly active against the tested microorganisms. The correlation between antimicrobial activity and the chemical structure of phenothiazines was discussed.

Keywords

Keywords: Antimicrobial

monoazaphenothiazine

phenothiazine

microorganisms

structure –activity relationship.

Manuscript

pdf Antimicb work of Phenothiazine.pdf

Poster

pdf Antimicb work of Phenothiazine.pdf

Synthesis of New Derivatives of Monoazaphenothiazine via Tandem Catalysis

Synthesis of α-aminophosphonates and related derivatives under microwave conditions