EventsThe 21st International Electronic Conference on Synthetic Organic Chemistry
Event submissions
Published
with-doi10.3390/ecsoc-21-04724
This submission belongs to the session D. Polymer and Supramolecular Chemistry of the event The 21st International Electronic Conference on Synthetic Organic Chemistry
Published date
03 Nov, 2017
Citation
Kamran Kazemi, Hanieh Rezazadeh, Amir Reza Fareghi, Peyman Najafi Moghadam, Synthesis and Characterization of a Melamine-modified Hydrogel: The Study of Doxorubicin Slow Release, in Proceedings of The 21st International Electronic Conference on Synthetic Organic Chemistry, 1 November–30 November 2017, MDPI: Basel, Switzerland, doi: 10.3390/ecsoc-21-04724
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Synthesis and Characterization of a Melamine-modified Hydrogel: The Study of Doxorubicin Slow Release

Kamran Kazemi 1
Hanieh Rezazadeh 1
Amir Reza Fareghi 1
Peyman Najafi Moghadam 1
1. Department of Chemistry, Faculty of Science, Urmia University, Urmia, Iran
Abstract

  In the present study, a melamine-modified hydrogel was synthesized for use as Doxorubicin delivery carrier. In the first step, poly(acrylic acid-co-maleic anhydride) was synthesized via free radical polymerization. Then the prepared copolymer was crosslinked by melamine to obtain the final carrier. The swelling behavior of the carrier was carried out afterwards. Moreover, different analyses such as FT-IR, TGA and SEM techniques were used to characterize the final polymer. In the final step, the Doxorubicin drug was loaded on the polymer and the slow-release study of the drug was investigated.

Keywords
Doxorubicin
Hydrogel
Copolymer
Drag delivery
Manuscript
kamran kazemi.pdf
Preparation of a New Magnetic Drug Carrier Based on Poly(vinyl alcohol): Synthesis, Characterization, and Drug Release Studies
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