EventsThe 14th International Electronic Conference on Synthetic Organic Chemistry
Event submissions
Published
with-doi10.3390/ecsoc-14-00474
This submission belongs to the session b. Natural Products Chemistry of the event The 14th International Electronic Conference on Synthetic Organic Chemistry
Published date
31 Oct, 2010
Citation
Eugenio Uriarte, Lourdes Santana, Giovanna Delogu, Maria Joao Matos, Silvia Serra, Synthesis of new possible monoamine oxidase inhibitors, in Proceedings of The 14th International Electronic Conference on Synthetic Organic Chemistry, 1 November–30 November 2010, MDPI: Basel, Switzerland, doi: 10.3390/ecsoc-14-00474
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Synthesis of new possible monoamine oxidase inhibitors

Eugenio Uriarte 1
Lourdes Santana 1
Giovanna Delogu 2
Maria Joao Matos 1
Silvia Serra 1,2
1. Department of Organic Chemistry, Faculty of Pharmacy, University of Santiago de Compostela, 15782 Santiago de Compostela, Spain
2. Department Farmaco Chimico Tecnologico, Facoltà di Farmacia, Università Degli Studi di Cagliari, Cagliari 09124, Italy.
Abstract
We have generated different resveratrol-coumarin hybrids with the aim of evaluate their biological applications and their pharmacological properties, particularly the inhibitory activity of monoamine oxidase enzyme. According to that, a first series of 3-aryl-4-hydroxycoumarins has been synthesized starting from aryl boronic acids and phenyliodonium zwitterions precursors by a palladium-catalyzed coupling reaction.
Keywords
coumarin
MAO
Suzuki reaction
2-Nitrobenzofuran and 3-Nitrobenzofurans as dienophiles in Polar Diels-Alder Reactions. Theoretical studies using DFT Methods
NITROSUBSTITUTED 1,2-PHENYLENEDIAMINES