EventsThe 21st International Electronic Conference on Synthetic Organic Chemistry
Published
This submission belongs to the session A. General Organic Synthesis of the event The 21st International Electronic Conference on Synthetic Organic Chemistry
Published date
07 Nov, 2017
Citation
Victor V. Dotsenko, Maria P. Goykalova (Averyasova), Elena A. Chigorina, Inna V. Aksenova, Nikolay A. Aksenov, Vladimir D. Strelkov, A new approach towards thieno[2,3-h][1,6]naphthyridines, in Proceedings of The 21st International Electronic Conference on Synthetic Organic Chemistry, 1 November–30 November 2017, MDPI: Basel, Switzerland, doi: 10.3390/ecsoc-21-04852
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A new approach towards thieno[2,3-h][1,6]naphthyridines

Maria P. Goykalova (Averyasova) 1
Elena A. Chigorina 4
Inna V. Aksenova 3
Vladimir D. Strelkov 1,5
1. Kuban State University, 149 Stavropolskaya Str., Krasnodar 350040, Russian Federation
2. ChemEx Lab, Vladimir Dal’ Lugansk National University, Lugansk, 91034 Russia.
3. North-Caucasus Federal University, 1 Pushkina St., 355009 Stavropol, Russian Federation
4. Federal State Unitary Enterprise «Research Institute of Chemical Reactants and Ultrapure Compounds (IREA)», 3 Bogorodsky Shaft, Moscow 107076, Russia
5. All-Russian Research Institute of Biological Plant Protection, Laboratory of plant growth regulators, 350039 Krasnodar, Russian Federation
Abstract

Triethylammonium salts of (4-aryl-3-cyano-6-oxo-1,4,5,6-tetrahydropyridin-2-yl)malononitriles were prepared by reaction of aldehydes with Meldrum's acid and 2-amino-1,1,3-tricyanopropene (malononitrile dimer) in the presence of triethylamine. Upon treatment with alpha-mercaptocarbonyl compounds in the presence of alkali, new thieno[2,3-h][1,6]naphthyridines were prepared in good yields.

Keywords
Meldrum's acid
2-amino-1,1,3-tricyanopropene
malononitrile dimer
thieno[2,3-h][1,6]naphthyridines
Manuscript
Organoselenium Chemistry: after 200 years the "Gold Rush" is still open
Synthesis of new functionalized thieno[2,3-b]pyridines