EventsThe 14th International Electronic Conference on Synthetic Organic Chemistry
Event submissions
Published
with-doi10.3390/ecsoc-14-00490
This submission belongs to the session b. Natural Products Chemistry of the event The 14th International Electronic Conference on Synthetic Organic Chemistry
Published date
02 Nov, 2010
Citation
M. Khalil, Samir M. El-Rayes, M. Y. El-Kady, M. E. Abd El-Fattah, Synthesis and Biological Evaluation of Some Coumarin Derivatives, in Proceedings of The 14th International Electronic Conference on Synthetic Organic Chemistry, 1 November–30 November 2010, MDPI: Basel, Switzerland, doi: 10.3390/ecsoc-14-00490
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Synthesis and Biological Evaluation of Some Coumarin Derivatives

M. Khalil 1
Samir M. El-Rayes 1
M. Y. El-Kady 2
M. E. Abd El-Fattah 1
1. Department of Chemistry, Faculty of Science, Suez Canal University, Ismailia, Egypt.
2. -Department of Chemistry, Faculty of Science, Ain Shams University, Cairo, Egypt.
Abstract
Starting from 7-hydroxy-4-methylcoumarin which was prepared via pechmann condensation, some comarin derivatives were synthesized depending on several reactions which are condensation with aldehydes, Mannich reaction, alkylation and reaction with hydrazine hydrate. The prepared compounds were evaluated for their microbiological activity against Grame +ve bacteria Bacillus Subtilis, Gram –ve bacteria Serratia marcenses and fungi Trichoderma Sp.
Keywords
7-hydroxy-4-methylcoumarin
7-hydroxy-4-styryl-2H-chromen-2-one
antimicrobial activity
Synthesis and Properties of some N-acyl ethylenediamine triacetic acid Chelating Surfactants
Evidence of cyclodextrin aggregation obtained with Fluorescence Correlation Spectroscopy