EventsMOL2NET'17, Conference on Molecular, Biomed., Comput. & Network Science and Engineering, 3rd ed.
Published
This submission belongs to the session 03. USEDAT-03: USA-EU Data Analysis Training Prog. Work., Cambridge, UK-Bilbao, Spain-Duluth, USA, 2017 of the event MOL2NET'17, Conference on Molecular, Biomed., Comput. & Network Science and Engineering, 3rd ed.
Published date
23 Jan, 2018
Citation
Viviana Quevedo, Alejandro Pazos-Sierra, Bernabé Ortega-Tenezaca, Humbert González-Díaz, Julio César Vargas-Burgos, Prediction of RIFIN proteins with gene orientation network indices, in Proceedings of MOL2NET'17, Conference on Molecular, Biomed., Comput. & Network Science and Engineering, 3rd ed., 15 January–15 December 2017, MDPI: Basel, Switzerland, doi: 10.3390/mol2net-03-05124
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Prediction of RIFIN proteins with gene orientation network indices

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Julio César Vargas-Burgos 2
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1. RNASA-IMEDIR, Computer Science Faculty, University of A Coruña, 15071, A Coruña, Spain
2. Universidad Estatal Amazónica
3. Dept. of Organic Chemistry II, University of the Basque Country UPV/EHU, 48940, Leioa, Biscay, Spain
Abstract

Gene orientation may have a direct influence on the expression of genes. In this work, we developed a Linear Discriminant Analysis (LDA) model able to predict RIFIN-like proteins of out of 5365 of Plasmodium falciparum proteins with Sensitivity and Specificity 70-80% in training and external validation series.

Keywords
Malaria
Plasmodium sp. proteome
Chromosome microstructure
Gene orientation
Complex Networks
Machine Learning
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