EventsThe 22nd International Electronic Conference on Synthetic Organic Chemistry
Event submissions
Published
with-doi10.3390/ecsoc-22-05665
This submission belongs to the session C. General Organic Synthesis of the event The 22nd International Electronic Conference on Synthetic Organic Chemistry
Published date
14 Nov, 2018
Citation
Nguyen Dinh Thanh, Do Son Hai, Pham Thi Thu Hien, Vu Thi Ngoc Bich, Vu Ngoc Toan, Hoang Thi Kim Van, Tran Thi Thanh Van, Study on the synthesis of some (un)substituted 2-amino-4-aryl-7-hydroxy-4H-chromene-3-carbonitriles in the water medium, in Proceedings of The 22nd International Electronic Conference on Synthetic Organic Chemistry, 15 November–15 December 2018, MDPI: Basel, Switzerland, doi: 10.3390/ecsoc-22-05665
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Study on the synthesis of some (un)substituted 2-amino-4-aryl-7-hydroxy-4H-chromene-3-carbonitriles in the water medium

Nguyen Dinh Thanh 1
Do Son Hai 2
Pham Thi Thu Hien 3
Vu Thi Ngoc Bich 3
Vu Ngoc Toan 4
Hoang Thi Kim Van 5
Tran Thi Thanh Van 3
1. Faculty of Chemistry, VNU Hanoi University of Science, 19 Le Thanh Tong, Hanoi (Vietnam)
2. Institute of Technique in Chemistry, Biology and Security Documents (Ministry of Public Security, Vietnam)
3. Faculty of Chemistry, VNU University of Science (Vietnam National University, Ha Noi), 19 Le Thanh Tong, Hoan Kiem, Ha Noi, Viet Nam
4. Institute for Chemistry and Materials, Military Institute of Science and Technology, 17 Hoang Sam, Cau Giay, Ha Noi, Viet Nam
5. Viet Tri University of Industry, Tien Kien, Lam Thao, Phu Tho, Viet Nam
Abstract

An efficient and simple synthesis of substituted 2-amino-4H-chromene-3-carbonitriles was developed by the one-pot and three-component reaction of a mixture of corresponding substituted benzaldehydes, resorcinol, and malononitrile in the presence of sodium carbonate solution as a catalyst at room temperature.

Keywords
2-amino-4H-chromene-3-carbonitriles
propargyl ethers
potassium carbonate
SN2
Manuscript
Chromene synthesis-Manuscript (ECSOC-22).pdf
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