EventsThe 22nd International Electronic Conference on Synthetic Organic Chemistry
Event submissions
Published
with-doi10.3390/ecsoc-22-05668
This submission belongs to the session C. General Organic Synthesis of the event The 22nd International Electronic Conference on Synthetic Organic Chemistry
Published date
14 Nov, 2018
Citation
Murali Venkata Basavanag Unnamatla, Rocío Gámez Montaño, Efficient and rapid conversion of 3-amino imidazo[1,2-a] pyridin-2-yl)-4H-chromene-4-ones to its corresponding thio analogues using Lawesson’s reagent , in Proceedings of The 22nd International Electronic Conference on Synthetic Organic Chemistry, 15 November–15 December 2018, MDPI: Basel, Switzerland, doi: 10.3390/ecsoc-22-05668
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Efficient and rapid conversion of 3-amino imidazo[1,2-a] pyridin-2-yl)-4H-chromene-4-ones to its corresponding thio analogues using Lawesson’s reagent

Murali Venkata Basavanag Unnamatla 1,2
Rocío Gámez Montaño 3
1. Centro Conjunto de Investigacion en Química Sustentable UAEM-UNAM, Toluca, Estado de Mexico, Mexico.
2. Facultad de Quimica , Universidad Autonoma del Estado de Mexico
3. Universidad de Guanajuato
Abstract

An expeditious, efficient and high yield conversion of ketone group in GBB adducts was obtained by the reaction with 3-formyl chromone, 2-amino pyridine and isocyanide to corresponding thio analogues is described utilizing Lawesson’s reagent. The reaction was involved microwave irradiation for both GBBR and the functional group transformation from ketone to thio ketone using Lawesson’s reagent in a one-pot fashion. The thio heterocyclic analogs of GBB products were characterized by using IR, NMR, and HRMS.

Keywords
GBB reaction
Lawesson’s reagent
3-formyl chromone
thio chromones
Manuscript
sciforum-022183.pdf
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