Events The 22nd International Electronic Conference on Synthetic Organic Chemistry

Event submissions

Published

This submission belongs to the session C. General Organic Synthesis of the event The 22nd International Electronic Conference on Synthetic Organic Chemistry

Published date

14 Nov, 2018

Citation

Mahanandaiah Kurva, Murali Venkata Basavanag Unnamatla, María del Rocio Gámez Montaño, Solvent free synthesis of imidazo [1,2-a] pyridin- tetrazolo [1,5-a] quinolones via a IMCR one-pot process., in Proceedings of The 22nd International Electronic Conference on Synthetic Organic Chemistry, 15 November–15 December 2018, MDPI: Basel, Switzerland, doi: 10.3390/ecsoc-22-05796

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Solvent free synthesis of imidazo [1,2-a] pyridin- tetrazolo [1,5-a] quinolones via a IMCR one-pot process.

Mahanandaiah Kurva ¹

Murali Venkata Basavanag Unnamatla ¹

María del Rocio Gámez Montaño ¹

1. Universidad de Guanajuato, División de Ciencias Naturales y Exactas, Departamento de Química

Abstract

Solvent-catalyst free synthesis of poly-heterocycles containing imidazo[1,2-a]pyridine and Tetrazolo[1,5-a]quinoline frameworks via a one-pot process: IMCR Groebke-Blackburn-Bienaymé reaction (GBBR)/S_NAr/ ring-chain azido tautomerization under ecofriendly conditions. The Tetrazolo[1,5-a]quinoline and imidazo [1,2-a] pyridine scaffolds are the structural core of various compounds with interesting pharmacological properties and could lead to the discovery of novel bioactive molecules.

Keywords

Isocyanide based multicomponent reactions

Groebke-Blackburn-Bienaymé reaction

Tetrazolo [1,5-a] quinolines

ring-chain azido tautomerization

one-pot process.

Manuscript

article ECSOC 22th ID-022345.pdf

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