EventsThe 22nd International Electronic Conference on Synthetic Organic Chemistry
Event submissions
Published
with-doi10.3390/ecsoc-22-05798
This submission belongs to the session C. General Organic Synthesis of the event The 22nd International Electronic Conference on Synthetic Organic Chemistry
Published date
14 Nov, 2018
Citation
Murali Venkata Basavanag Unnamatla, María del Rocio Gámez Montaño, Sandra Cecilia Ramírez López, A One-pot process for the synthesis of Alkyne-3-tretrazolyl-tetrazolo [1,5-a] quinolines., in Proceedings of The 22nd International Electronic Conference on Synthetic Organic Chemistry, 15 November–15 December 2018, MDPI: Basel, Switzerland, doi: 10.3390/ecsoc-22-05798
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A One-pot process for the synthesis of Alkyne-3-tretrazolyl-tetrazolo [1,5-a] quinolines.

Sandra Cecilia Ramírez López 1
Murali Venkata Basavanag Unnamatla 1
María del Rocio Gámez Montaño 1
1. Universidad de Guanajuato, División de Ciencias Naturales y Exactas, Departamento de Química
Abstract

An efficient synthesis of alkyne-3-tetrazolyl-Tetrazolo[1,5-a] quinolone via a one-pot process: I-MCR Ugi-azide /SNAr/ ring-chain azido tautomerization under ecofriendly conditions. We report the one-pot synthesis of tris-heterocycles containing the tetrazolo[1,5-a]quinoline bound with 1,5-disubstituted-tetrazole (1,5-DS-T). The synthesis of this compounds can be of high interest for synthetic and medicinal chemistry because all the heterocycles are considered privilegied scaffolds and could lead to the discovery of novel bioactive molecules.

Keywords
Isocyanide based multicomponent reactions
Ugi-azide
Tetrazolo [1,5-a] quinolines
ring-chain azido tautomerization
one-pot process.
Manuscript
article ECSOC 22th ID-022351.pdf
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