EventsMOL2NET'18, Conference on Molecular, Biomed., Comput. & Network Science and Engineering, 4th ed.
Event submissions
Published
with-doi10.3390/mol2net-04-06133
This submission belongs to the session 03. CHEMBIOINFO-04: Chem-Bioinformatics Congress Cambridge, UK-Chapel Hill and Duluth, USA, 2018 of the event MOL2NET'18, Conference on Molecular, Biomed., Comput. & Network Science and Engineering, 4th ed.
Published date
13 Jan, 2019
Citation
Abdmlouleh Fatma, Mehdi El Arbi, Maité Sylla-Iyarreta Veitía, Mamdouh Ben Ali, Clotilde Ferroud, Structure-antimicrobial activity relationship of a series of functionalized arylbenzothiazoles , in Proceedings of MOL2NET'18, Conference on Molecular, Biomed., Comput. & Network Science and Engineering, 4th ed., 15 January 2018–20 January 2019, MDPI: Basel, Switzerland, doi: 10.3390/mol2net-04-06133
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Structure-antimicrobial activity relationship of a series of functionalized arylbenzothiazoles

Abdmlouleh Fatma 1,2
Mehdi El Arbi 2
image
Maité Sylla-Iyarreta Veitía 1
Mamdouh Ben Ali 2
Clotilde Ferroud 1
1. Equipe de Chimie Moléculaire du Laboratoire CMGPCE, EA 7341, Conservatoire national des arts et métiers, 2 rue Conté,75003, HESAM Université, Paris France
2. Laboratoire de Biotechnologie Microbienne et d’Ingénierie des Enzymes (LBMIE). Centre de Biotechnologie de Sfax, Université de Sfax, Route de Sidi Mansour Km 6, BP 1177, 3018 Sfax, Tunisie
Abstract

The antibacterial activity of a series of functionalized arybenzothiazoles was investigated against Gram-positive pathogens including Staphylococcus aureus (ATCC 9144), Micrococcus luteus (LB14110), Salmonella enterica (NCTC 6017) and Gram-negative foodborne Pseudomonas aeruginosa (ATCC 9027), Escherichia coli (ATCC 8739). The antifungal activity was also evaluated against the opportunistic pathogenic yeast Candida albicans (ATCC 2091). The results displayed that these compounds exhibit a good antimicrobial activity compared with fusidic acid. The structure-antimicrobial activity relationships are also discussed

Keywords
arylbenzothiazoles
antibacterial activity
antifungal
Manuscript
BioChemPhys BenzothiazolesVFf 05_01.pdf
Poster
BioChemPhys BenzothiazolesVFf 05_01.pdf
BioChemPhys BenzothiazolesVFf 05_01.pdf
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