EventsMOL2NET'19, Conference on Molecular, Biomed., Comput. & Network Science and Engineering, 5th ed.
Event submissions
Published
with-doi10.3390/mol2net-05-06267
This submission belongs to the session 07. CHEMBIOMOL-05: Chem. Biol. & Med. Chem. Workshop, Bilbao-Lisboa, Portugal-Rostock, Germany, Galveston, Texas, USA, 2019 of the event MOL2NET'19, Conference on Molecular, Biomed., Comput. & Network Science and Engineering, 5th ed.
Published date
08 Oct, 2019
Citation
MUHAMMAD FARMAN, Noshin Nasreen, Nabil Semmar, Saud Nasim Ahmad, Gas Chromatography aided Mass Spectral Fingerprinting of Volatile Phytoconstituents from Torilis leptophylla Roots, in Proceedings of MOL2NET'19, Conference on Molecular, Biomed., Comput. & Network Science and Engineering, 5th ed., 20 March–20 December 2019, MDPI: Basel, Switzerland, doi: 10.3390/mol2net-05-06267
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Gas Chromatography aided Mass Spectral Fingerprinting of Volatile Phytoconstituents from Torilis leptophylla Roots

Noshin Nasreen 1
Nabil Semmar 2
MUHAMMAD FARMAN 1
Saud Nasim Ahmad 3
1. Department of Chemistry, Quaid-i-Azam University, Islamabad-45320, PAKISTAN
2. University of Tunis El Manar, Institut Pasteur de Tunis, Laboratory of BioInformatics, BioMathematics & BioStatistics, Tunisia
3. Sharif Medical & Dental College, Jati Umra, Sharif Medical City Road, Lahore, Pakistan
Abstract

Torilis leptophylla commonly known as bristle fruit hedge parsley is widely acknowledged for its potential to treat liver and gastrointestinal disorders. Till today no scientific evidence has been reported to support this claim. So the present investigation was carried out to get an inclusive picture of volatile phytoconstituents of Torilis leptophylla. Hyphenated chromatographic technique revealed the presence of 11 VOC’s from n-Hexane extract and 5 from chloroform extract. Identified compounds belonged to different classes including terpenes, esters, phenols, hydrocarbons and alcohols. Among alcohols, falcarinol was revealed to be a de-novo antifungal agent not previously reported in the genus Torilis. These analytical/structural chemical investigations highlighted a first metabolic pattern associated with the use of this plant as a folk medicine for the cure of various infectious diseases. Moreover, they ratified that the metabolic pool of phytochemicals can play a noteworthy role in drug discovery and development.

Keywords
Torilis leptophylla
Volatile Phytoconstituents
GC-MS
Falcarinol
Manuscript
TORILIS LETOPHYLLA GC-MS SCRIPT 08-10-2019.pdf
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