Event submissions
Published
This submission belongs to the session A. ECMC-5 of the event 5th International Electronic Conference on Medicinal Chemistry
Published date
30 Oct, 2019
Citation
Ann Burdeynaya, Elena Bibik, Bogdan Krivokolysko, Konstantin Frolov, Victor Dotsenko, Sergey Krivokolysko, Influence of partially hydrogenated pyridines (derivatives of cyanothioacetamide) on blood indicators of rats with acute tetrachloromethane hepatitis, in Proceedings of 5th International Electronic Conference on Medicinal Chemistry, 1 November–30 November 2019, MDPI: Basel, Switzerland, doi: 10.3390/ECMC2019-06304
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Influence of partially hydrogenated pyridines (derivatives of cyanothioacetamide) on blood indicators of rats with acute tetrachloromethane hepatitis
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Ann Burdeynaya 1
Elena Bibik 2
Bogdan Krivokolysko 2
Konstantin Frolov 2
Victor Dotsenko 2
Sergey Krivokolysko 2
1. St. Luke Lugansk State Medical University, Ukraine
2. St. Luke Lugansk State Medical University
Abstract
Currently, a focused search for new and safe hepatoprotective agents is highly relevant. Studies of six partially hydrogenated pyridines, derivatives of cyanothioacetamide, on a model of acute tetracycline hepatitis indicated a high hepatoprotective and detoxifying activity for all compounds. They stabilized the level of biochemical blood parameters, keeping them at the normal level in terms of hepatotoxicity induced by the use of high dosages of CCl4 in vivo.
Keywords
Hepatoprotective agents
carbon tetrachloride
hydrogenated pyridines
cyanothioacetamide
Manuscript
Influence of partially hydrogenated pyridines (derivatives of cyanothioacetamide) on blood indicators of rats with acute tetrachloromethane hepatitis_.pdf
Oral Presentation
Influence_of_partially_hydrogenated.ppt
Poster
Influence-of-partially-hydrogenated-pyridines-_derivatives-of-cyanothioacetamide_-on-blood-indicator.pdf
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