Events The 23rd International Electronic Conference on Synthetic Organic Chemistry

Event submissions

Published

This submission belongs to the session A. General Organic Synthesis of the event The 23rd International Electronic Conference on Synthetic Organic Chemistry

Published date

14 Nov, 2019

Citation

Thies Thiemann, Abdullah Al-Hemyari, Hanan Rashid Aldhanhani, Halima Alawani, Amnah Othman Al Hmoudi, Fatima Hamad Aljunaibi, Deuteration of alkenes with NaBD₄/AcOD in presence of Pd on carbon, in Proceedings of The 23rd International Electronic Conference on Synthetic Organic Chemistry, 15 November–15 December 2019, MDPI: Basel, Switzerland, doi: 10.3390/ecsoc-23-06461

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Deuteration of alkenes with NaBD₄/AcOD in presence of Pd on carbon

Fatima Hamad Aljunaibi ¹

Hanan Rashid Aldhanhani ¹

Halima Alawani ¹

Amnah Othman Al Hmoudi ¹

Abdullah Al-Hemyari ¹

Thies Thiemann ²

1. Department of Chemistry, UAE University

2. Department of Chemistry, United Arab Emirates University

Abstract

Activated alkenes such as cinnamates and chalcones can easily be converted to 2,3-dideuterio-arylpropionates and dideuteriochalcones, respectively, by the action of NaBD₄, AcOD in the presence of Pd on carbon. Toluene or benzene was used as solvent. It was shown that Pd on carbon was necessary for the reaction to proceed. Deuterium addition experiments were also carried out with NaBD₄, AcOD, D₂O in the presence of Pd on carbon

Keywords

deuterium addition

in situ deuterium production

sodium borodeuteride

Manuscript

ECSOC-2019-deuteration (1).pdf

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Deuteration of alkenes with NaBD4/AcOD in presence of Pd on carbon

Deuteration of alkenes with NaBD₄/AcOD in presence of Pd on carbon