EventsThe 23rd International Electronic Conference on Synthetic Organic Chemistry
Published
This submission belongs to the session D. Polymer and Supramolecular Chemistry of the event The 23rd International Electronic Conference on Synthetic Organic Chemistry
Published date
14 Nov, 2019
Citation
Manik Ghosh, Harish Kumar Singh, Rojalini Samanta, BIOACTIVE GRAFT CO-POLYMER FOR THE TREATMENT OF BREAST CANCER, in Proceedings of The 23rd International Electronic Conference on Synthetic Organic Chemistry, 15 November–15 December 2019, MDPI: Basel, Switzerland, doi: 10.3390/ecsoc-23-06512
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BIOACTIVE GRAFT CO-POLYMER FOR THE TREATMENT OF BREAST CANCER

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1. Department of Pharmaceutical Sciences and Technology, Birla Institute of Technology, Mesra, Ranchi, Jharkhand (835215), INDIA
Abstract

Cancer is one of the most researched areas nowadays due to the increasing incidences of cancer patients and unavailability of cheap and highly efficient drugs. Cancer is the uncontrolled proliferation of the body’s own cell. The cancer cells are dedifferentiated and lose their normal function. We are aware of the fact that the cancer cells differ from normal cells in many aspects. One such aspect is pH of cancer cells. The cancer cell has a pH lower than that of the normal cells of the body. In this research, we have prepared target-specific and pH-sensitive bioactive polymer using a combination of different natural polymer like polyvinyl alcohol, sodium alginate in a different ratios. Since, these polymers are pH sensitive, they will release the loaded drug only at the cancer site thus reducing the various side effects of the drug and drug toxicity.

Keywords
Cancer
bioactive polymers
pH sensitive polymer
Manuscript
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