Events The 23rd International Electronic Conference on Synthetic Organic Chemistry

Event submissions

Published

This submission belongs to the session A. General Organic Synthesis of the event The 23rd International Electronic Conference on Synthetic Organic Chemistry

Published date

14 Nov, 2019

Citation

MANUEL ALEJANDRO RENTERIA GOMEZ, MARIA DEL ROCÍO GÁMEZ MONTAÑO, Synthesis of the 2-tetrazolylmethyl-2,3,4,9-tetrahydro-1H-b-carbolines via ultrasound-assisted one-pot Ugi-azide/Pictet–Spengler process, in Proceedings of The 23rd International Electronic Conference on Synthetic Organic Chemistry, 15 November–15 December 2019, MDPI: Basel, Switzerland, doi: 10.3390/ecsoc-23-06515

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Synthesis of the 2-tetrazolylmethyl-2,3,4,9-tetrahydro-1H-b-carbolines via ultrasound-assisted one-pot Ugi-azide/Pictet–Spengler process

MANUEL ALEJANDRO RENTERIA GOMEZ ¹

MARIA DEL ROCÍO GÁMEZ MONTAÑO ²

1. Universidad de Guanajuato, División de Ciencias Naturales y Exactas, Departamento de Química, Mexico

2. Universidad de Guanajuato, División de Ciencias Naturales y Exactas, Departamento de Química

Abstract

A serie of 2-tetrazolylmethyl-2,3,4,9-tetrahydro-1H-b-carbolines were synthesized via a one pot Ugi-azide/Pictet–Spengler process under mild ultrasound-assisted conditions. The products containing two privileged heterocyclic frameworks: 1,5- disubstituted-1H-tetrazole and tetrahydro-b-carboline, which are present in a variety of bioactive compounds and commercial drugs.

Keywords

Ugi-azide/Pictet–Spengler

ultrasound-assisted

1,5- disubstituted-tetrazole

b-carboline

Manuscript

ECSOC.pdf

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