Events The 23rd International Electronic Conference on Synthetic Organic Chemistry

Event submissions

Published

This submission belongs to the session A. General Organic Synthesis of the event The 23rd International Electronic Conference on Synthetic Organic Chemistry

Published date

14 Nov, 2019

Citation

Victor V Dotsenko, Alena Russkih, Nicolai Aksenov, Inna Aksenova, SYNTHESIS OF NEW 2-OXO-1,2-DIHYDROPYRIDINE-3-CARBOXYLIC ACID DERIVATIVES, in Proceedings of The 23rd International Electronic Conference on Synthetic Organic Chemistry, 15 November–15 December 2019, MDPI: Basel, Switzerland, doi: 10.3390/ecsoc-23-06523

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SYNTHESIS OF NEW 2-OXO-1,2-DIHYDROPYRIDINE-3-CARBOXYLIC ACID DERIVATIVES

Victor V Dotsenko ^1,2,3

Alena Russkih ⁴

Nicolai Aksenov ³

Inna Aksenova ³

1. Department of Organic Chemistry and Technologies, Kuban State University, 149 Stavropolskaya Str., 350040 Krasnodar, Russia

2. ChemEx Lab, Vladimir Dal’ Lugansk National University

3. North Caucasus Federal University

4. Kuban State University

Abstract

2,2-Dimethyl-5-((phenylamino)methylene)-1,3-dioxane-4,6-dione prepared by reaction of Meldrum’s acid with triethyl orthoformate and aniline, reacts with active methylene nitriles to afford 2-oxo-1,2-dihydropyridine-3-carboxylic acid derivatives useful as drug precursors or perspective ligands.

Keywords

nicotinic acids

Meldrum’s acid

2-oxo-1,2-dihydropyridine-3-carboxylic acid

cyanothioacetamide

cyanoacetamide.

Manuscript

annl_tezisy.pdf

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