EventsThe 23rd International Electronic Conference on Synthetic Organic Chemistry
Event submissions
Published
with-doi10.3390/ecsoc-23-06656
This submission belongs to the session A. General Organic Synthesis of the event The 23rd International Electronic Conference on Synthetic Organic Chemistry
Published date
16 Nov, 2019
Citation
Biljana M Smit, Petar Stanic, Marija Zivkovic, Zoran Ratkovic, Jovana Muskinja, Thiohydantoins from vanillin and its derivatives - Synthesis and Characterization, in Proceedings of The 23rd International Electronic Conference on Synthetic Organic Chemistry, 15 November–15 December 2019, MDPI: Basel, Switzerland, doi: 10.3390/ecsoc-23-06656
Share
Email
Facebook
Twitter
LinkedIn

Thiohydantoins from vanillin and its derivatives - Synthesis and Characterization

Petar Stanic 1
Marija Zivkovic 2
Zoran Ratkovic 1
Jovana Muskinja 3
Biljana M Smit 3
1. Faculty of Science, University of Kragujevac, Radoja Domanovića 12 P.O. Box 60, 34000 Kragujevac, Serbia
2. Faculty of Medical Sciences, University of Kragujevac, Svetozara Markovica 69, 34000 Kragujevac, Serbia
3. Institute for Information Technologies Kragujevac, Department of Science, University of Kragujevac, Jovana Cvijica bb, 34000 Kragujevac, Serbia
Abstract

Hydantoins and their sulfur containing analogues, thiohydantoins, are an important and interesting moiety. They represent a big group of structurally diverse compounds with intriguing physical, chemical and biological properties, which enabled them to be used in therapy, medicine in general, material science and industry.

With the goal of broadening the set of potentially applicable hydantoin derivatives, we have synthesized a series of 2-thiohydantoins from vanillin and its derivatives, which themselves posses interesting biological properties. All compounds were fully characterized by NMR and IR spectroscopy. The compounds will be subjected to intensive biological screening to determine their biological properties and application opportunities.

Keywords
thiohydantoins
synthesis
vanillin
Manuscript
ECSOC23 Biljana Smit.pdf
Synthesis of AlF3 as a catalyst of Heck reaction
Ionic liquid mediated Ugi/SN2 Cyclization: Synthesis of 1,2,3-Triazole containing novel 2,5-diketopiperazines.