Events The 15th International Electronic Conference on Synthetic Organic Chemistry

Event submissions

Published

This submission belongs to the session a. General Organic Synthesis of the event The 15th International Electronic Conference on Synthetic Organic Chemistry

Published date

17 Oct, 2011

Citation

Bassam al-Hindawi, Yousef Al-Jasem, Mazen al-Sulaibi, Thies Thiemann, Replacement of Tetrachloromethane with Bromotrichloromethane in Appel-type reactions, in Proceedings of The 15th International Electronic Conference on Synthetic Organic Chemistry, 1 November–30 November 2011, MDPI: Basel, Switzerland, doi: 10.3390/ecsoc-15-00674

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Replacement of Tetrachloromethane with Bromotrichloromethane in Appel-type reactions

Bassam al-Hindawi ¹

Yousef Al-Jasem ²

Mazen al-Sulaibi ¹

Thies Thiemann ¹

1. Department of Chemistry, United Arab Emirates University, Al Ain, United Arab Emirates

2. Faculty of Engineering, United Arab Emirates University, Al Ain, United Arab Emirates

Abstract

The authors report on the use of the reaction system BrCCl₃/PPh₃ in the amidation of carboxylic acids, in the preparation of anhydrides from carboxylic acids and in the esterification of carboxylic acids with cholesterol, where cinnamic acids were used as acid component in all three transformations. Furthermore, the use of BrCCl₃/PPh₃ in the dehydration of benzcarboxamides to benzonitriles was studied as well as the preparation of N-(phenylsulfonyl)-triphenylphosphoranylideneamide from benzenesulfonamide.

Keywords

Appel-type reaction

bromotriochloromethane

cinnamides

cholesteryl cinnamates

Theoretical study of the mechanisms of the decomposition of ethyl and ethyl 3-phenyl glycidate

Reductive amination of aldehydes using a lithium-arene(cat.) reducing system. A simple one-pot procedure for the synthesis of secondary amines.