EventsMOL2NET'20, Conference on Molecular, Biomed., Comput. & Network Science and Engineering, 6th ed.
Published
This submission belongs to the session 10. NANOBIOMATJND-06: JSU-NDSU Nanotech. & BioMaterials Workshop, Jackson & Fargo, USA, 2020 of the event MOL2NET'20, Conference on Molecular, Biomed., Comput. & Network Science and Engineering, 6th ed.
Published date
09 Apr, 2020
Citation
Debbethi Bera, Kunal Pal, Parimal Karmakar, Sukhen Das, Papiya Nandy, Highly Fluorescent Carbon Nanoparticle: An Emerging Bioimaging Intervention, in Proceedings of MOL2NET'20, Conference on Molecular, Biomed., Comput. & Network Science and Engineering, 6th ed., 30 January 2020–30 January 2021, MDPI: Basel, Switzerland, doi: 10.3390/mol2net-06-06786
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Highly Fluorescent Carbon Nanoparticle: An Emerging Bioimaging Intervention

Debbethi Bera 1,2
Parimal Karmakar 5
Sukhen Das 1,2
1. Centre for Interdisciplinary Research and Education, 404B, Jodhpur Park, Kolkata-700068, India
2. Department of Physics, Jadavpur University, Kolkata-700032, India
3. Department of Life Science and Biotechnology, Jadavpur University, Kolkata-700032, India
4. Division of Molecular Medicine and Centre for Translational Research, Bose Institute, Kolkata-700056, India
5. Department of Life Science and Biotechnology, Jadavpur University, Kolkata-700032, India
Abstract

Carbon nanoparticles are known because of their highly fluorescent property. Thus, among several different types of nanoparticles, carbon nanoparticles have great potential of bio imaging applications. Highly fluorescent crystalline carbon nanoparticles (CNPs) have been synthesized in a facile, rapid method which involves microwave irradiation of sucrose with phosphoric acid at 100 W for 4 mins. Hence this method is fleet and cost effective for large scale applications. Physical characterization of synthesized CNPs was done by DLS and Zeta potential, Hydrodynamic size of CNPs as measured by DLS was 281.2 d.nm. The surface charge of carbon nanoparticles was found to be -39.7 mV. These CNPs have green fluorescence under UV exposure. CNPs enter into cell without any further modification and show their efficiency as fluorescence based cell imaging application. Further, we have explored the antibacterial property of carbon nanoparticles by Minimum Inhibitory Concentration (MIC).

Keywords
Carbon nanoparticles
Fluorescence
Cell labeling
RBC
Breast Cancer cell.
Manuscript
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