EventsMOL2NET'20, Conference on Molecular, Biomed., Comput. & Network Science and Engineering, 6th ed.
Published
This submission belongs to the session 02. USINEWS-04: US-IN-EU Worldwide Science Workshop Series, Duluth, USA, 2020 of the event MOL2NET'20, Conference on Molecular, Biomed., Comput. & Network Science and Engineering, 6th ed.
Published date
11 Apr, 2020
Citation
Tathagata Dey, Subhamoy Biswas, Shreyans Chatterjee, Smarajit Manna, Ashesh Nandy, Subhas C Basak, 2D Polar Co-ordinate Representation of Amino Acid Sequences With some applications to Ebola virus, SARS and SARS-CoV-2 (COVID-19), in Proceedings of MOL2NET'20, Conference on Molecular, Biomed., Comput. & Network Science and Engineering, 6th ed., 30 January 2020–30 January 2021, MDPI: Basel, Switzerland, doi: 10.3390/mol2net-06-06790
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2D Polar Co-ordinate Representation of Amino Acid Sequences With some applications to Ebola virus, SARS and SARS-CoV-2 (COVID-19)

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Shreyans Chatterjee 2,4
Smarajit Manna 2,5
1. Computer Science Department, Government College of Engineering and Textile Technology, Serampore-712201, India, India
2. Centre for Interdisciplinary Research and Education, Kolkata-700068, India
3. Electrical Engineering Department, Jadavpur University, Kolkata-700032, India
4. Microbiology Department, St. Xavier’s College, Kolkata-700016, India
5. Jagadis Bose National Science Talent Search, Kolkata 700107, India
6. Department of Chemistry and Biochemistry, University of Minnesota, Duluth, MN, USA; sbasak@d.umn.edu
Abstract

We consider a novel approach to mathematically define a graphing method to represent amino acid sequences of proteins in two-dimensional plane and characterize them numerically. The amino acids are represented by their relative magnitude of their hydrophobicity. Each amino acid is compared with a vector and moves in relative direction which generates a graph. Applications are shown in Zaire Ebola Virus to conclude how this plotting can be more useful than base sequence plotting. Also, superimposition graph of SARS and SARS-CoV-2 shows that these sequences are strongly related and Various other applications are shown too to explain it's fruitfulness.

Keywords
Protein Graph
Graphical Representation
Numerical Characterization
Polar Coordinate
Polar Plot
Amino Acid
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