EventsMOL2NET'20, Conference on Molecular, Biomed., Comput. & Network Science and Engineering, 6th ed.
Event submissions
Published
with-doi10.3390/mol2net-06-06880 (registering DOI)
This submission belongs to the session 01. CHEMBIOMOL-06: Chem. Biol. & Med. Chem. Workshop, Bilbao-Rostock, Germany-Galveston, Texas, USA, 2020 of the event MOL2NET'20, Conference on Molecular, Biomed., Comput. & Network Science and Engineering, 6th ed.
Published date
17 Jul, 2020
Citation
Deyani Nocedo-Mena, Elvira Garza-González, María del Rayo Camacho-Corona, Promising activity of Cissus incisa extracts against Mycobacterium Tuberculosis H37RV strain, in Proceedings of MOL2NET'20, Conference on Molecular, Biomed., Comput. & Network Science and Engineering, 6th ed., 30 January 2020–30 January 2021, MDPI: Basel, Switzerland, doi: 10.3390/mol2net-06-06880
Share
Email
Facebook
Twitter
LinkedIn

Promising activity of Cissus incisa extracts against Mycobacterium Tuberculosis H37RV strain

Deyani Nocedo-Mena 1
image
Elvira Garza-González 2
María del Rayo Camacho-Corona 3
1. Autonomous University of Nuevo León, Faculty of Sciences. Av. Universidad S / N, University City, CP 66451, San Nicolás de los Garza, Nuevo León, México, Mexico
2. Autonomous University of Nuevo León, Gastroenterology Service, University Hospital Dr. José Eleuterio González. Av. Gonzalitos y Madero S/N, Colonia Mitras Centro, CP 64460, Monterrey, Nuevo León, México
3. Autonomous University of Nuevo León, Faculty of Sciences. Av. Universidad S / N, University City, CP 66451, San Nicolás de los Garza, Nuevo León, México
Abstract

Tuberculosis (TB) is a bacterial infection caused by the bacillus Mycobacterium tuberculosis. It usually affects the lungs, but it can also affect other sites (extrapulmonary TB).

In the “Global Tuberculosis Report 2018”, TB is recognized as one of the 10 main causes of death worldwide and the main cause of a single infectious agent (above HIV/AIDS).

By the other hand, medicinal plants have been widely used to treat this disease. Some extracts derived from plants are known to have antimycobacterial properties, and can be of great significance in therapeutic treatments. For that reason, we aimed to evaluate the antimycobacterial activity of Cissus incisa leaves on a sensible strain. Three extracts were prepared from collected leaves of this plant: hexane, chloroform methanol (1:1) and aqueous. The antitubercular activity was evaluated on M. Tuberculosis H37RV strain (ATCC), using Alamar Blue assay. The hexane and chloroform/methanol extracts were the most active (MIC=250 μg/mL). Until the best of our knowledge, there are no studies related to the traditional use of this plant for treat tuberculosis.

The present investigation will contribute to the discovery of potential antibacterial agents derived from plants, and to expand the use of C. incisa in traditional medicine.

Keywords
Tuberculosis
Mycobacterium tuberculosis
extracts
Manuscript
Promising activity of Cissus incisa extracts against Mycobacterium Tuberculosis H37RV strain.pdf
Poster
Promising activity of Cissus incisa extracts against Mycobacterium Tuberculosis H37RV strain.pdf
Promising activity of Cissus incisa extracts against Mycobacterium Tuberculosis H37RV strain.pdf
In silico protein-protein interaction: C-phycocyanin has potential for block proliferation and adhesion proteins in cancer
Microalgae pigment with possible anti-caries activity: In silico evidences