Events The 15th International Electronic Conference on Synthetic Organic Chemistry

Event submissions

Published

This submission belongs to the session a. General Organic Synthesis of the event The 15th International Electronic Conference on Synthetic Organic Chemistry

Published date

25 Oct, 2011

Citation

Victor Victorovich Dotsenko, Elena Anatolyevna Chigorina, Synthesis of Triethylammonium 4-Aryl-3,5-dicyano-6-oxo-1,4,5,6-tetrahydropyridine-2-olates: 1-Cyanoacetyl-3,5-dimethylpyrazole as an Effective Alternative to Cyanoacetic Ester in Guareschi Reaction, in Proceedings of The 15th International Electronic Conference on Synthetic Organic Chemistry, 1 November–30 November 2011, MDPI: Basel, Switzerland, doi: 10.3390/ecsoc-15-00702

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Synthesis of Triethylammonium 4-Aryl-3,5-dicyano-6-oxo-1,4,5,6-tetrahydropyridine-2-olates: 1-Cyanoacetyl-3,5-dimethylpyrazole as an Effective Alternative to Cyanoacetic Ester in Guareschi Reaction

Victor Victorovich Dotsenko ¹

Elena Anatolyevna Chigorina ^2,3

1. ChemEx Laboratory, Vladimir Dal’ East Ukrainian National University, kv Molodezhny 20-A 7/309, 91034 Lugansk

2. Chemical Diversity Research Institute, 2a-1 Rabochaya St., Khimki, Moscow region, 141400 Russia

3. Research Institute of Plastics, Perovsky proezd 35, 111024, Moscow, Russia

Abstract

Triethylammonium 4-aryl-3,5-dicyano-6-oxo-1,4,5,6-tetrahydropyridine-2-olates were obtained by reaction of (E)-3-aryl-2-cyanoacrylamides with 1-cyanoacetyl-3,5-dimethylpyrazole in the presence of 1.5 eq. of Et₃N (20 °C, acetone) in 55-98% yields.

Keywords

Guareschi reaction

1-cyanoacetyl-3,5-dimethylpyrazole

Ab-initio Study on the Stabilities and Structures of Monosilacyclopropylidenoids

Influence of the substitution on the inversion barrier of corannulene: a theoretical study.