EventsThe 15th International Electronic Conference on Synthetic Organic Chemistry
Event submissions
Published
with-doi10.3390/ecsoc-15-00772
This submission belongs to the session a. General Organic Synthesis of the event The 15th International Electronic Conference on Synthetic Organic Chemistry
Published date
31 Oct, 2011
Citation
M. Reza Naimi-Jamal, Narges Ghadaksaz, Mohammad G. Dekamin, A Facile Biginelli Reaction on Grinding Using Nano-Ordered MCM-41-SO3H as an Efficient Solid Acid Catalyst, in Proceedings of The 15th International Electronic Conference on Synthetic Organic Chemistry, 1 November–30 November 2011, MDPI: Basel, Switzerland, doi: 10.3390/ecsoc-15-00772
Share
Email
Facebook
Twitter
LinkedIn

A Facile Biginelli Reaction on Grinding Using Nano-Ordered MCM-41-SO3H as an Efficient Solid Acid Catalyst

M. Reza Naimi-Jamal 1
Narges Ghadaksaz 1
Mohammad G. Dekamin 1
1. Depatment of Chemistry, Iran University of Science & Technology, Tehran, 16848-13114, Iran
Abstract
A facile protocol for the one-pot synthesis of pyrimidinone derivatives through Biginelli reaction in the presence of catalytic amount of the nano-ordered MCM-41-SO3H anchored sulfonic acid (MCM-41-SO3H) has been described. The reaction proceeds smoothly under solvent-free conditions on grinding of a mixture of different aldehydes, ethyl acetoacetate and urea in a mortar.
Keywords
Biginelli Reaction
Nano-Ordered Solid Acid
Multicomponent Reaction (MCR)
Grinding
Green Chemistry
Substituent Effect on the Aromaticity of 1,3-Azole Systems
Synthetic studies on tulearin macrolides