EventsThe 24th International Electronic Conference on Synthetic Organic Chemistry
Event submissions
Published
with-doi10.3390/ecsoc-24-08391
This submission belongs to the session A. General Organic Synthesis of the event The 24th International Electronic Conference on Synthetic Organic Chemistry
Published date
14 Nov, 2020
Citation
Victor V Dotsenko, Karina Khalatyan, Alena Russkih, Aminat M. Semenova, New quinoxaline-1,4-dioxides derived from Beirut reaction of benzofuroxane with active methylene nitriles, in Proceedings of The 24th International Electronic Conference on Synthetic Organic Chemistry, 15 November–15 December 2020, MDPI: Basel, Switzerland, doi: 10.3390/ecsoc-24-08391
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New quinoxaline-1,4-dioxides derived from Beirut reaction of benzofuroxane with active methylene nitriles

Victor V Dotsenko 1,2,3
Karina Khalatyan 4
Alena Russkih 4
Aminat M. Semenova 4,5
1. Department of Organic Chemistry and Technologies, Kuban State University, 149 Stavropolskaya Str., 350040 Krasnodar, Russia
2. ChemEx Lab, Vladimir Dal’ Lugansk National University
3. North Caucasus Federal University
4. Kuban State University
5. North-Caucasus State Humanitarian Technological Academy, 36 Stavropolskaya St., Cherkessk 369000, Karachay-Cherkess Republic, Russia
Abstract

Benzofuroxane reacts under Beirut reaction conditions with active methylene nitriles to give new 2-aminoquinoxaline-1,4-dioxides. Treatment of known 2-amino-3-cyanoquinoxaline-1,4-dioxide with chloroacetyl chloride afforded corresponding chloroacetamide useful for preparation of various heterocycles bearing quinoxaline-1,4-dioxide core system.

Keywords
Beirut reaction
benzofuroxane
2-aminoquinoxaline-1,4-dioxides
hetarylacetonitriles
malononitrile
Manuscript
GeneralOrganicSynthesis_8391_New_quinoxaline_1_4_dioxides_d_done.pdf
Key Intermediates for introducing a bulky bicyclo[3.3.0]heptane skeleton in the w-side chain to reduce the enzyme inactivation of prostaglandins
STUDY OF A NEW HYDRAZONE SYSTEM WITH ION COMPLEXATION CAPACITY SUITABLE FOR SELECTIVE DETECTION.