EventsThe 24th International Electronic Conference on Synthetic Organic Chemistry
Event submissions
Published
with-doi10.3390/ecsoc-24-08396
This submission belongs to the session A. General Organic Synthesis of the event The 24th International Electronic Conference on Synthetic Organic Chemistry
Published date
14 Nov, 2020
Citation
Sandra Cecilia Ramírez López, Manuel Alejandro Rentería-Gómez, María del Rocío Gámez Montaño, Cesar R. Solorio Alvarado, Synthesis of peptidomimetics via IMCR/post-transformation strategy, in Proceedings of The 24th International Electronic Conference on Synthetic Organic Chemistry, 15 November–15 December 2020, MDPI: Basel, Switzerland, doi: 10.3390/ecsoc-24-08396
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Synthesis of peptidomimetics via IMCR/post-transformation strategy

Sandra Cecilia Ramírez López 1
Manuel Alejandro Rentería-Gómez 1
María del Rocío Gámez Montaño 1
Cesar R. Solorio Alvarado 1
1. Universidad de Guanajuato, División de Ciencias Naturales y Exactas, Departamento de Química
Abstract

A series of three 2,5-diketopiperazine (DKP’s) were synthesized via one-pot process through the post-IMCR-transformation strategy. This strategy emphasizes the role of orthogonal bifunctional reagents in the IMCR process to increase their synthetic potential, allowing us accessing a synthetic platform from which it is possible to obtain privileged heterocyclic peptidomimetics via lactamization reaction.

Keywords
2,5-diketopiperazine (DKP’s)
Ugi-4CR/lactamization
peptidomimetics
Manuscript
GeneralOrganicSynthesis_8396-done.pdf
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