EventsThe 24th International Electronic Conference on Synthetic Organic Chemistry
Event submissions
Published
with-doi10.3390/ecsoc-24-08403
This submission belongs to the session A. General Organic Synthesis of the event The 24th International Electronic Conference on Synthetic Organic Chemistry
Published date
14 Nov, 2020
Citation
Anatoly Shutalev, Alexander N. Yankov, A new synthesis of 3-arylideneamino- and 3-alkylideneamino-substituted hydantoins, in Proceedings of The 24th International Electronic Conference on Synthetic Organic Chemistry, 15 November–15 December 2020, MDPI: Basel, Switzerland, doi: 10.3390/ecsoc-24-08403
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A new synthesis of 3-arylideneamino- and 3-alkylideneamino-substituted hydantoins

Alexander N. Yankov 1
Anatoly Shutalev 2
1. N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47 Leninsky Ave., 119991 Moscow, Russian Federation
2. N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47 Leninsky Ave., 119991 Moscow, Russian Federation, Russia
Abstract

A novel straightforward approach to 3-arylideneamino- and 3-alkylideneaminohydantoins has been developed. It is based on reaction of readily available 4-(tosylmethyl)semicarbazones with NaCN in DMF followed by heating of the obtained α-(4-semicarbazono)nitriles with conc. HCl.

Keywords
4-(tosylmethyl)semicarbazones
α-amidoalkylation
α-(4-semicarbazono)nitriles
3-aminohydantoins
Manuscript
GeneralOrganicSynthesis_8403_A_new_synthesis_of_3_arylidene_original-done.pdf
SYNTHESIS OF BENZO[b]CARBAZOLS BY TANDEM Au(I)-CATALYZED CYCLIZATION/MIGRATION/CYCLIZATION
Novel semicarbazone-based α-amidoalkylating reagents: general synthesis and reactions with H-, O-, S-, N-, and P-nucleophiles