Events The 24th International Electronic Conference on Synthetic Organic Chemistry

Event submissions

Published

This submission belongs to the session A. General Organic Synthesis of the event The 24th International Electronic Conference on Synthetic Organic Chemistry

Published date

14 Nov, 2020

Citation

Victor V Dotsenko, Vyacheslav S. Muraviev, Ludmila V. Dyadyuchenko, Nicolai Aksenov, The reaction of malononitrile dimer with 4-methyl-2,6-dichloronicotinonitrile, in Proceedings of The 24th International Electronic Conference on Synthetic Organic Chemistry, 15 November–15 December 2020, MDPI: Basel, Switzerland, doi: 10.3390/ecsoc-24-08418

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The reaction of malononitrile dimer with 4-methyl-2,6-dichloronicotinonitrile

Victor V Dotsenko ^1,2,3

Vyacheslav S. Muraviev ^4,5

Ludmila V. Dyadyuchenko ⁵

Nicolai Aksenov ³

1. Department of Organic Chemistry and Technologies, Kuban State University, 149 Stavropolskaya Str., 350040 Krasnodar, Russia

2. ChemEx Lab, Vladimir Dal’ Lugansk National University

3. North Caucasus Federal University

4. Kuban State University

5. Federal State Budgetary Scientific Institution "All-Russian Research Institute of Biological Plant Protection", Krasnodar-39, Krasnodar, 350039, Russia

Abstract

The reaction of 4-methyl-2,6-dichloronicotinonitrile with malononitrile dimer (2-amino-1,1,3-tricyanopropene) in the presence of triethylamine leads to regioselective nucleophilic substitution of the chlorine atom at position 6 and the formation of triethylammonium 2-amino-3-(4-methyl-6-chloro-5-cyanopyridin-2-yl)-1,1,3-tricyanoprop-2-en-1-ide. The structure of the product was confirmed by X-ray studies.

Keywords

2,6-dichloronicotinonitrile

malononitrile dimer

nucleophilic substitution

triethylamine

Manuscript

GeneralOrganicSynthesis_8418-done.pdf

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