EventsThe 24th International Electronic Conference on Synthetic Organic Chemistry
Event submissions
Published
with-doi10.3390/ecsoc-24-08429
This submission belongs to the session D. Polymer and Supramolecular Chemistry of the event The 24th International Electronic Conference on Synthetic Organic Chemistry
Published date
14 Nov, 2020
Citation
Dana Miu, Mariana Gratiela Vladu, Sorin Ion Jinga, STUDIES ON MCL-POLYHYDROXYALKANOATES USING DIFFERENT CARBON SOURCES FOR NEW BIOMEDICAL MATERIALS., in Proceedings of The 24th International Electronic Conference on Synthetic Organic Chemistry, 15 November–15 December 2020, MDPI: Basel, Switzerland, doi: 10.3390/ecsoc-24-08429
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STUDIES ON MCL-POLYHYDROXYALKANOATES USING DIFFERENT CARBON SOURCES FOR NEW BIOMEDICAL MATERIALS.

Dana Miu 1,2
Mariana Gratiela Vladu 3
Sorin Ion Jinga 1
1. University Politehnica of Bucharest, Faculty of Applied Chemistry and Materials Science, 1-7 Gh. Polizu Street, 01106, Bucharest, Romania
2. National Institute for Chemical Pharmaceutical Research and Development, 112 Vitan Ave, 031299, Bucharest, Romania
3. National Institute for Chemical Pharmaceutical Research and Development, 112 Vitan Ave, 031299, Bucharest, Romania
Abstract

Polyhydroxyalkanoates (PHAs) are microbial homo- and copolymers of [R]-β-hydroxyalkanoic acids, produced by a wide variety of bacteria as an intracellular carbon and energy reserve. To obtain mcl-PHAs of microbial origin we used a Pseudomonas spp. strain (from the National Institute for Chemical-Pharmaceutical Research and Development (ICCF) culture collection of micro-organisms), by varying the carbon sources and the precursors.

In this work, assays were performed with fermentation media seeded with inoculum cultures of strain Pseudomonas putida in a proportion of 10%.

The influence on mcl -PHA production of carbon sources for strain development, hexanoic (C6), heptanoic (C7), octanoic (C8) and nonanoic (C9) acids, as polymers precursors, were analyzed. Due to their properties, similar to those of conventional plastics and to their biodegradability, PHAs are suitable for many applications and for biomedical materials useful in surgical sutures, tissue engineering and drugs carriers, which leads us to the deepening of the study of obtaining micro/nanofibers by the electrospinning method.

Keywords
polyhydroxyalkanoates
bioprocess
biomaterials
electrospinning
Manuscript
PolymerandSupramolecularChemistry_8429_STUDIES_ON_MCL_POLYHYDROXYALKA_done.pdf
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