Event submissions
Published
10.3390/PCMS-08969 (registering DOI) This submission belongs to the session 1. Biomaterials and Soft Materials of the event First Poster Competition on Materials Science
Published date
08 Jan, 2021
Citation
Jithender J. Timothy, Vijaya Holla, Günther Meschke, Drusen Growth in Age-Related Macular Degeneration: A Computational Analysis, in Proceedings of First Poster Competition on Materials Science, 20 January 2021, MDPI: Basel, Switzerland, doi: 10.3390/PCMS-08969
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Drusen Growth in Age-Related Macular Degeneration: A Computational Analysis
Vijaya Holla 1
Jithender J. Timothy 2
Günther Meschke 1
1. Ruhr University Bochum
2. Ruhr University Bochum, Germany
Abstract
Age-related macular degeneration (AMD) is a disease that causes progressive loss of sharp central vision. AMD is characterized by the presence of extracellular debris called drusen. In this contribution, the effect of drusen size on the morphological changes in the layers of the outer retina i.e. RPE, BrM and photoreceptors is investigated using the cellular potts model (CPM) and methods of machine learning. Numerical simulation of the influence of drusen growth and its effect on the morphology of the outer retinal layers of the macula is presented.
Keywords
vision loss
blindness
AMD
drusen
retina
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