EventsThe 1st International Electronic Conference on Cancers: Exploiting Cancer Vulnerability by Targeting the DNA Damage Response
Event submissions
Published
with-doi10.3390/IECC2021-09213
This submission belongs to the session 8. Poster of the event The 1st International Electronic Conference on Cancers: Exploiting Cancer Vulnerability by Targeting the DNA Damage Response
Published date
29 Jan, 2021
Citation
Bishoy M. F. Hanna, Torkild Visnes, Carlos Benitez-Buelga, Oliver Mortusewicz, Kumar Sanjiv, Geoffrey Masuyer, Olov Wallner, Maurice Michel, Olga Loseva, Ann-Sofie Jemth, Christina Kalderen, Pal Stenmark, Ulrika Warpman Berglund, Thomas Helleday, Armando Cazares-Körner, Targeting OGG1 as a Novel Anti-Cancer Strategy, in Proceedings of The 1st International Electronic Conference on Cancers: Exploiting Cancer Vulnerability by Targeting the DNA Damage Response, 1 February–14 February 2021, MDPI: Basel, Switzerland, doi: 10.3390/IECC2021-09213
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Targeting OGG1 as a Novel Anti-Cancer Strategy

Bishoy M. F. Hanna 1
Torkild Visnes 1,2
Carlos Benitez-Buelga 1
Armando Cazares-Körner 1
Kumar Sanjiv 1
Oliver Mortusewicz 1
Geoffrey Masuyer 3,4
Olov Wallner 1
Maurice Michel 1
Olga Loseva 1
Ann-Sofie Jemth 1
Christina Kalderen 1
Pal Stenmark 3,5
Ulrika Warpman Berglund 1
Thomas Helleday 1,6
1. Science for Life Laboratory, Department of Oncology and Pathology, Karolinska Institutet, S-171 76 Stockholm, Sweden
2. Department of Biotechnology and Nanomedicine, SINTEF Industry, N-7465 Trondheim, Norway
3. Department of Biochemistry and Biophysics, Stockholm University, SE-106 91 Stockholm, Sweden
4. Department of Pharmacy and Pharmacology, Centre for Therapeutic Innovation. University of Bath, Bath BA2 7AY, UK
5. Department of Experimental Medical Science, Lund University, SE-221 00 Lund, Sweden
6. Weston Park Cancer Centre, Department of Oncology and Metabolism, University of Sheffield, Sheffield S10 2RX, UK
Abstract
Keywords
DNA damage response
oxidative DNA damage
base excision repair
OGG1 glycosylase
OGG1 inhibitor
TH5487
cancer
replication stress